Details for gene set NCI_IL2-MEDIATED SIGNALING EVENTS[GSEA]

Table: GSEA Results Summary

Dataset	Set_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy_repos
Phenotype	phenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos
Upregulated in class	normalThy
GeneSet	NCI_IL2-MEDIATED SIGNALING EVENTS
Enrichment Score (ES)	-0.6219053
Normalized Enrichment Score (NES)	-1.5980217
Nominal p-value	0.0
FDR q-value	0.09830717
FWER p-Value	0.772

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	RPS6	2060168	135	4.476	0.0258	No
2	MAPKAPK2	2850500	616	2.672	0.0195	No
3	STAT5A	2680458	905	2.165	0.0200	No
4	GRB2	6650398	957	2.091	0.0327	No
5	JAK3	70347 3290008	1371	1.655	0.0226	No
6	BCL3	3990440	1455	1.580	0.0297	No
7	E2F1	5360093	1632	1.410	0.0306	No
8	HRAS	1980551	1652	1.391	0.0399	No
9	PPP2R5D	4010156 380408 5550112 5670162	2115	1.024	0.0225	No
10	SOCS3	5550563	2282	0.957	0.0206	No
11	UBE2D3	3190452	2294	0.950	0.0270	No
12	NFKB1	5420358	2322	0.926	0.0324	No
13	CYLD	6590079	2761	0.674	0.0137	No
14	IL2RA	6620450	2842	0.642	0.0141	No
15	TNF	6650603	3118	0.530	0.0031	No
16	PRKCZ	3780279	3165	0.512	0.0044	No
17	RAC1	4810687	3509	0.390	-0.0112	No
18	ELF1	4780450	3596	0.357	-0.0132	No
19	STAM	3850008 4760441	3619	0.346	-0.0119	No
20	MALT1	4670292	3693	0.324	-0.0134	No
21	PRKCA	6400551	3738	0.311	-0.0135	No
22	CCNA2	5290075	3772	0.303	-0.0130	No
23	REL	360707	3934	0.268	-0.0197	No
24	KRAS	2060170	4016	0.250	-0.0223	No
25	RPS6KB1	1450427 5080110 6200563	4328	0.202	-0.0376	No
26	BIRC2	2940435 4730020	4414	0.189	-0.0408	No
27	MAP2K2	4590601	4513	0.178	-0.0448	No
28	SOS1	7050338	4633	0.165	-0.0500	No
29	INSL3	4150092	5258	0.115	-0.0829	No
30	RIPK2	5050072 6290632	5335	0.111	-0.0861	No
31	MAPK11	130452 3120440 3610465	5405	0.107	-0.0891	No
32	IL4	6020537	5544	0.100	-0.0958	No
33	RASA1	1240315	5862	0.084	-0.1123	No
34	ATM	3610110 4050524	6074	0.076	-0.1232	No
35	PIK3R1	4730671	7165	0.043	-0.1817	No
36	RAN	2260446 4590647	7457	0.038	-0.1972	No
37	AKT1	5290746	7808	0.031	-0.2159	No
38	MYC	380541 4670170	8103	0.025	-0.2316	No
39	XPO1	540707	8282	0.022	-0.2410	No
40	MAP2K1	840739	8442	0.019	-0.2495	No
41	NRAS	6900577	8445	0.019	-0.2494	No
42	CALM1	380128	8847	0.013	-0.2710	No
43	PTPN11	2230100 2470180 6100528	9168	0.008	-0.2883	No
44	GAB2	1410280 2340520 4280040	9538	0.002	-0.3082	No
45	ARRB2	2060441	9730	-0.001	-0.3185	No
46	PIK3CA	6220129	9883	-0.003	-0.3267	No
47	SRC	580132	11142	-0.022	-0.3945	No
48	PRKCE	5700053	11229	-0.024	-0.3990	No
49	HSP90AA1	4560041 5220133 2120722	11231	-0.024	-0.3989	No
50	NOD2	2510050	11446	-0.027	-0.4102	No
51	IL2	1770725	11676	-0.032	-0.4224	No
52	CHUK	7050736	11886	-0.036	-0.4334	No
53	FBXW11	6450632	11951	-0.037	-0.4366	No
54	IRS1	1190204	12187	-0.043	-0.4490	No
55	IFNG	5670592	13106	-0.070	-0.4981	No
56	SGMS1	4780195	13571	-0.091	-0.5225	No
57	SYK	6940133	13785	-0.106	-0.5332	No
58	TERT	6660075	13920	-0.115	-0.5396	No
59	SHC1	2900731 3170504 6520537	14198	-0.138	-0.5535	No
60	FRAP1	2850037 6660010	14493	-0.168	-0.5682	No
61	JUN	840170	14564	-0.175	-0.5707	No
62	STAT5B	6200026	14806	-0.214	-0.5821	No
63	MAPK1	3190193 6200253	14867	-0.227	-0.5837	No
64	ERC1	1580170 2630717 6110762 6840280	14877	-0.230	-0.5825	No
65	FOS	1850315	15011	-0.260	-0.5877	No
66	FOXO3	2510484 4480451	15027	-0.263	-0.5866	No
67	STAM2	730731 2120377	15085	-0.277	-0.5876	No
68	CDK6	4920253	15196	-0.305	-0.5913	No
69	FASLG	2810044	15237	-0.321	-0.5911	No
70	PRF1	6660309	15336	-0.350	-0.5938	No
71	MAPK3	580161 4780035	15356	-0.356	-0.5922	No
72	IKBKG	3450092 3840377 6590592	15419	-0.375	-0.5928	No
73	IKBKB	6840072	15462	-0.391	-0.5922	No
74	LTA	1740088	15617	-0.457	-0.5972	No
75	SP1	6590017	16076	-0.696	-0.6168	Yes
76	CALM2	6620463	16171	-0.751	-0.6163	Yes
77	MAPK8	2640195	16187	-0.761	-0.6115	Yes
78	JAK1	5910746	16259	-0.809	-0.6094	Yes
79	FYN	2100468 4760520 4850687	16323	-0.850	-0.6065	Yes
80	MAPK9	2060273 3780209 4070397	16570	-1.002	-0.6124	Yes
81	MYB	1660494 5860451 6130706	16734	-1.112	-0.6130	Yes
82	IL2RB	4730072	16881	-1.233	-0.6118	Yes
83	BCL2	730132 1570736 2470138 3800044 4810037 5690068 5860504 6650164	16927	-1.270	-0.6048	Yes
84	FOXP3	940707 1850692	16933	-1.277	-0.5957	Yes
85	SMPD1	1410309 5550717	17039	-1.400	-0.5910	Yes
86	NFKB2	2320670	17059	-1.421	-0.5815	Yes
87	MAPK14	5290731	17073	-1.446	-0.5716	Yes
88	CDK2	130484 2260301 4010088 5050110	17116	-1.496	-0.5628	Yes
89	TRAF6	4810292 6200132	17171	-1.553	-0.5542	Yes
90	BCL2L1	1580452 4200152 5420484	17203	-1.597	-0.5441	Yes
91	RELA	3830075	17220	-1.623	-0.5330	Yes
92	RAF1	1770600	17237	-1.646	-0.5217	Yes
93	MAP3K14	5890435	17267	-1.682	-0.5109	Yes
94	RELB	1400048	17302	-1.724	-0.5000	Yes
95	RHOA	580142 5900131 5340450	17313	-1.730	-0.4877	Yes
96	UGCG	3420053	17501	-2.035	-0.4828	Yes
97	CALM3	3390288	17601	-2.209	-0.4719	Yes
98	LCK	3360142	17665	-2.357	-0.4579	Yes
99	SOCS2	4760692	17782	-2.591	-0.4450	Yes
100	STAT1	6510204 6590553	17835	-2.706	-0.4278	Yes
101	DOK2	5340273	18026	-3.162	-0.4147	Yes
102	BCL10	2360397	18036	-3.190	-0.3917	Yes
103	NFKBIA	1570152	18160	-3.680	-0.3711	Yes
104	STAT3	460040 3710341	18169	-3.701	-0.3443	Yes
105	SOCS1	730139	18267	-4.197	-0.3185	Yes
106	IL2RG	4120273	18336	-4.588	-0.2883	Yes
107	CCND3	380528 730500	18358	-4.702	-0.2547	Yes
108	CISH	840315	18477	-5.810	-0.2182	Yes
109	PTK2B	4730411	18521	-6.456	-0.1728	Yes
110	TNFAIP3	2900142	18562	-7.402	-0.1204	Yes
111	TNFRSF1A	1090390 6520735	18584	-8.303	-0.0602	Yes
112	CCND2	5340167	18589	-8.378	0.0015	Yes